Clicking thru the interface

So I have been having an issue of clicking thru the interface in L2. By that I mean when I click on the mail/party/quest... icons my mouse will click under them and I will run to that spot. This is somewhat annoying. It isn't 100% of the time. I've been trying to figure out what is causing this issue but haven't had any luck so far. I've been thru about 3 or 4 graphic card driver updates and that hasn't seemed to resolve the issue. This was happening with Windows 7 and even now with clean install of Windows 10.

Anyone out there have a fix or solution for this problem? Is anyone else dealing with the same problem?

Thanks for your help!

Clicking thru the interface